Protein editing

Masaharu Somiya
Last updated on May 11, 2026 protein editing

Protein editing is a method to directly modify protein sequence. Recently we developed a new method for post-translational sequence editing for protein using intein. This method allows us to precisely modify protein sequence in living cells, opens up new opportunities for synthetic biology and therapeutics.

Reference

  1. M. Somiya and T. Yanase, “Programmable protein editing by split intein-mediated recombination,” bioRxiv, Jan. 2026, doi: 10.64898/2026.01.22.700961.
  2. L. Tang, “Protein Editing,” Nat Methods, vol. 22, no. 12, pp. 2493–2493, Dec. 2025, doi: 10.1038/s41592-025-02951-5.
protein design protein editing
Masaharu Somiya
Masaharu Somiya
Associate Professor

My research interests include protein design for intracellular drug delivery, nanoparticle design, and synthetic biology.

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